A 12 male patient came to the hospital with complaints of pain in right arm. After evaluation the patient was diagnosed as osteosarcoma right humerus. After discussion with team in Tumor Board we had advised him for neo adjuvant chemotherapy followed surgery and adjuvant chemotherapy. We have performed a wide excision of total humerus and reconstructed with total humerus mega prosthesis. The patient is happy and indepedent performing his daily routine normally for last 2 years.